GHK-Cu Topical Dosing Protocol | IVUSE+
YOUR PROTOCOL V1.0 // Topical

GHK-Cu
Dosing Protocol

Copper peptide cream for skin repair, collagen support, and rejuvenation. Apply topically once per day.
Concentration
2%
30gm total
Format
Topical Cream
Pump bottle
Frequency
Once Daily
Morning or evening
Application
1–2 pumps
Face, neck, or target area
[01]

Daily Application

Follow these steps each day for optimal absorption and results.

  • Cleanse skin and pat dry. Start with clean, dry skin for best absorption.
  • Dispense 1–2 pumps onto your fingertips.
  • Apply evenly to face, neck, or target area. Use gentle, upward strokes. Avoid direct contact with eyes.
  • Allow 1–2 minutes to absorb. Wait until the cream feels dry before layering other products.
  • Follow with moisturizer to seal in the peptide.
  • Apply SPF if used in the morning. Daily sunscreen protects newly forming collagen.
[02]

Skincare Layering

Apply GHK-Cu after cleansing and before heavier products. The cream absorbs best on bare, clean skin.

Recommended Order
Step 1
Cleanser
▸
Step 2
GHK-Cu Cream
▸
Step 3
Moisturizer
▸
AM Only
SPF
Avoid using at the same time as: Vitamin C creams, AHA/BHA acids, or retinol. These can degrade the copper peptide bond or increase irritation. Use them on alternate nights or separate AM/PM.
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[03]

What to Expect

Copper peptides work progressively. Allow 12 weeks of consistent use before evaluating full results.

Timeline Expected Changes
1–2Weeks Reduced redness and inflammation. Improved hydration and skin feel.
3–4Weeks More even skin tone. Subtle texture smoothing begins.
6–8Weeks Fine lines soften. Skin feels noticeably firmer and more resilient.
10–12Weeks Visible reduction in wrinkle depth. Peak collagen-building benefits.
Consistency matters more than quantity. One pump applied daily will outperform two pumps used sporadically.
[04]

Storage & Stability

Store your GHK-Cu cream refrigerated at 36–46°F (2–8°C) after opening to maintain potency. Keep away from direct sunlight.
Watch the color. A blue or copper tone is normal and indicates an active peptide bond. If the cream turns green or fades significantly, the copper bond is breaking down. Discontinue use and replace.
[05]

Support

Questions about your protocol, application, or anything else? Reach our team directly at support@ivuseplus.com. We typically respond within 24 hours.

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This protocol is for informational purposes. Consult your healthcare provider before beginning any peptide protocol. If you experience persistent redness, irritation, or discomfort at the application site, discontinue use and contact support.

IVUSE Protocol // GHK-Cu 2% // Topical