IVUSE / MOTS-C Dosing Protocol
YOUR PROTOCOL V2.0 // SubQ

MOTS-C Dosing
Protocol

Mitochondrial peptide subcutaneous injection protocol. Regulates metabolism and promotes weight loss. Inject in a fasted state, AM or PM.

First time injecting? View our step-by-step Injection Tutorial before your first dose.

Concentration
2 mg/mL
Per vial
Method
Subcutaneous
Abdomen or thigh
Frequency
7 days / week
Once daily, fasted AM or PM
Daily Dose
10 units
Do not exceed 10 units
Cycle
12 weeks on
2 weeks off
Supply
30 days
Per vial
[01]

Dosing Schedule

Inject 10 units once daily in a fasted state, 7 days per week for 12 weeks. You may inject in the AM or PM based on your preference and schedule. Do not exceed 10 units per injection.

Day Dose Frequency
Monday 10units 1x daily
Tuesday 10units 1x daily
Wednesday 10units 1x daily
Thursday 10units 1x daily
Friday 10units 1x daily
Saturday 10units 1x daily
Sunday 10units 1x daily
Tip: MOTS-C can be injected morning or evening. Choose whichever time you can stay consistent with. A fasted state optimizes absorption and metabolic signaling.
Do not exceed 10 units per injection. This is a fixed-dose protocol. Do not increase without provider guidance.
[02]

Cycle Structure

Run a 12-week on-cycle followed by a 2-week off-cycle. The off-period allows your mitochondrial signaling pathways to recalibrate for sustained metabolic benefits.

Cycle Timeline // 14 Weeks Total
W1
W2
W3
W4
W5
W6
W7
W8
W9
W10
W11
W12
W13
W14
On-Cycle (12 weeks)
Off-Cycle (2 weeks)
Do not skip the off-cycle. Continuous use can lead to diminished response over time. The off-period is essential for maintaining the metabolic benefits of MOTS-C.
Next Cycle

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Order your next vial before you run out so you're ready to continue on schedule.

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[03]

Daily Quick Reference

Follow these steps for each injection. If this is your first time, review the Injection Tutorial for a full walkthrough.

  • 01
    Wash hands thoroughly with soap and water.
  • 02
    Draw 10 units into your syringe. Do not exceed 10 units.
  • 03
    Clean the injection site with an alcohol swab. Rotate between abdomen and thigh.
  • 04
    Pinch the skin and insert the needle at a 45-degree angle.
  • 05
    Inject slowly to reduce any stinging sensation at the site.
  • 06
    Dispose of the syringe in a sharps container. Never recap or reuse needles.
[04]

Storage

Store your MOTS-C vial refrigerated at 36-46°F (2-8°C) after reconstitution. Keep away from direct sunlight. Unreconstituted vials can be stored at room temperature.
[05]

Support

Questions about your protocol, dosing, or anything else? Reach our team directly at support@ivuseplus.com. We typically respond within 24 hours.

Don't run out
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This protocol is for informational purposes. Consult your healthcare provider before beginning any peptide protocol. If you experience persistent redness, swelling, or discomfort at the injection site, discontinue use and contact support.

IVUSE Protocol // MOTS-C // SubQ